Best methods for depression
A ranking of both medication/nutrition and non-drug treatments for depression, major depressive disorder (MDD), etc.
Psychoterapy
Psychotherapy, a.k.a. talk therapy, is the treatment of a person's problems by (typically) conversing with another person, usually a psychologist. There is also Group psychotherapy.
Group psychotherapy
Group psychotherapy or group therapy is a form of Psychoterapy in which one or more therapists treat a small group of clients together as a group. The term can legitimately refer to any form of psychotherapy when delivered in a gr...
Citalopram
(1989)Citalopram (brand names: Celexa, Cipramil) is an antidepressant drug of the selective serotonin reuptake inhibitor (SSRI) class. It has U.S. Food and Drug Administration approval to treat major depression, which it received in 199...
Tianeptine
(1987)Tianeptine (brand names Stablon, Coaxil, Tianeurax, Aneptinex, Atinepte, Neluptin, Lyxit, Neluptin, Tialera, Tianesal, Tatinol, Tianeurax, Salymbra) is a drug used primarily in the treatment of major depressive disorder, although...
Vortioxetine
(2013)Vortioxetine (trade name Brintellix and Trintellix in Canada) is an atypical antidepressant (a serotonin modulator and stimulator) made by Lundbeck and Takeda. On September 30, 2013, it was approved by the U.S. FDA for the treatme...
Piracetam
Piracetam (sold under many brand names) is a nootropic drug in the racetams group, with chemical name 2-oxo-1-pyrrolidine acetamide. It shares the same 2-oxo-pyrrolidone base structure with pyroglutamic acid. Piracetam is a cyclic...
Armodafinil
(2007)Armodafinil (brand names Nuvigil, Acronite, R-Modawake, Artvigil, Waklert) is the enantiopure of the wakefulness-promoting agent, or eugeroic, modafinil (Provigil). It consists of just the (−)-(R)-enantiomer of the racemic modafin...
Vilazodone
(2011)Vilazodone (trade name Viibryd) is a serotonergic antidepressant developed by Clinical Data for the treatment of major depressive disorder. The chemical compound was originally developed by Merck KGaA (Germany). Vilazodone was app...
Fluoxetine (Prozac)
(1987)Fluoxetine (trade names Prozac, Sarafem, Seronil, Rapiflux, Selfemra, and other) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. Fluoxetine was discovered and developed by scientists from Eli Lilly...
SAM-e
S-Adenosyl methionine (SAM-e, SAMe, SAM, S-Adenosyl-L-methionine, AdoMet, ademetionine) is a common cosubstrate involved in methyl group transfers. SAM was first discovered in Italy by G. L. Cantoni in 1952. SAM-e has been used as...
Fluvoxamine
(1983)Fluvoxamine (brand names: Faverin, Fevarin, Floxyfral, Luvox, Solvay, and other) is a medication which functions as a selective serotonin reuptake inhibitor (SSRI) and σ1 receptor agonist. Fluvoxamine is used primarily for the tre...
Fish oil
Fish oil is oil derived from the tissues of oily fish. Fish oils contain the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), precursors of certain eicosanoids that are known to reduce inflammation i...
Escitalopram
(2002)Escitalopram, brand names Lexapro and Cipralex among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is approved by the U.S. Food and Drug Administration (FDA) for the treatment of adult...
Duloxetine
(2004)Duloxetine (brand names Cymbalta, Yentreve, and other) is a serotonin-norepinephrine reuptake inhibitor (SNRI) created by Eli Lilly. It is mostly prescribed for major depressive disorder, generalized anxiety disorder (GAD), fibrom...
Levomilnacipran
(2013)Levomilnacipran (brand name Fetzima) is an antidepressant approved for the treatment of major depressive disorder in the United States. It was developed by Forest Laboratories and Pierre Fabre Group, and was approved by the Food a...
Milnacipran
(1996)Milnacipran (brand names Ixel, Savella, Dalcipran, Toledomin) is a serotonin–norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. It is not approved for the clinical treatment of major depressiv...
Paroxetine
(1992)Paroxetine (trade name Paxil, Seroxat, Brisdelle, Pexeva, among others) is an antidepressant drug of the SSRI type. Paroxetine is used to treat major depression, obsessive-compulsive disorder, panic disorder, social anxiety, postt...
Modafinil
(1994)Modafinil (brand names Modiodal, Provigil, Modavigil, Vigil, Alertec, and other) is a wakefulness-promoting agent (or eugeroic) used for treatment of wakefulness disorders such as narcolepsy, shift work sleep disorder, and excessi...
Venlafaxine
(1993)Venlafaxine (brand names: Effexor, Effexor XR, LanvexinTrevilor, Efectin, Oriven, Velafax, and other) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. This means it increases the concentrations...
Desvenlafaxine
(2008)Desvenlafaxine (brand names: Pristiq, DESFAX), also known as O-desmethylvenlafaxine, is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class developed and marketed by Wyeth (now part of Pfizer). Desven...
Sertraline
(1991)Sertraline (brand names Zoloft, Lustral, and other) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It was introduced to the market by Pfizer in 1991. Sertraline is primarily prescribed for major d...
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Noopept
Noopept (Russian: Ноопепт; GVS-111, N-phenylacetyl-L-prolylglycine ethyl ester) is a peptide promoted and prescribed in Russia and neighbouring countries as a nootropic. The registered brand name Noopept (Ноопепт) is trademarked b...
Semax
(1994)Semax (Russian: Семакс) is a drug produced and prescribed mostly in Russia and Ukraine for a broad range of conditions but predominantly for its purported nootropic, neuroprotective, and neurogenic/neurorestorative properties. It...
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Candidates list: 2.
Candidates list: 2.
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