Should the government interfere in employer-employee relations?

Obviously, if left to their own devices, big corporations will take any advantage of employees that they can. And before unions, they did so. Blue collar workers do not sign individual contracts. The jobs are always take it or leave it. The Government needs to step in with some guidelines, especially regarding employee safety and working conditions. Minimum wage is also becoming a major issue that needs to be addressed by the Government. Vacations, leave, etc. are still left open. The US is one of the few developed nations, that does not guarantee vacation time.