Top safe to use
An auxiliary ranking to provide a rating area for medications and nutrition-related items.
1
Semax
(1994)Semax (Russian: Семакс) is a drug produced and prescribed mostly in Russia and Ukraine for a broad range of conditions but predominantly for its purported nootropic, neuroprotective, and neurogenic/neurorestorative properties. It...
1
Phosphatidylserine
Phosphatidylserine (abbreviated Ptd-L-Ser or PS) is an important phospholipid membrane component (i.e. component of the cell membrane) which plays a key role in cell cycle signaling, specifically in relationship to apoptosis. Phos...
1
Tianeptine
(1987)Tianeptine (brand names Stablon, Coaxil, Tianeurax, Aneptinex, Atinepte, Neluptin, Lyxit, Neluptin, Tialera, Tianesal, Tatinol, Tianeurax, Salymbra) is a drug used primarily in the treatment of major depressive disorder, although...
1
Dapoxetine
(2009)Dapoxetine (brand names: Priligy, Westoxetin, Vriligy, Kutub, Sustinex, Prolox, Scifil, Longus, Duratia, Pentenal-30, Lejam, Dumax, Prejac, Everlast) is the first compound developed specially for the treatment of premature ejacula...
5
Oseltamivir (Tamiflu)
(1999)Oseltamivir, marketed under the trade name Tamiflu, is an antiviral medication used to prevent and treat influenza A and influenza B (flu). The medication is taken orally. Tamiflu is the only pharmaceutical drug approved by FDA to...
5
Fish oil
Fish oil is oil derived from the tissues of oily fish. Fish oils contain the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), precursors of certain eicosanoids that are known to reduce inflammation i...
7
Caffeine
Caffeine is a central nervous system (CNS) stimulant of the methylxanthine class of psychoactive drugs. It is the world's most widely consumed psychoactive drug, but unlike many other psychoactive substances, it is legal and unreg...
7
Armodafinil
(2007)Armodafinil (brand names Nuvigil, Acronite, R-Modawake, Artvigil, Waklert) is the enantiopure of the wakefulness-promoting agent, or eugeroic, modafinil (Provigil). It consists of just the (−)-(R)-enantiomer of the racemic modafin...
7
Noopept
Noopept (Russian: Ноопепт; GVS-111, N-phenylacetyl-L-prolylglycine ethyl ester) is a peptide promoted and prescribed in Russia and neighbouring countries as a nootropic. The registered brand name Noopept (Ноопепт) is trademarked b...
10
Zanamivir (Relenza)
(1989)Zanamivir is a neuraminidase inhibitor used in the treatment and prophylaxis of influenza caused by influenza A and B viruses. It was developed by the Australian biotech firm Biota Holdings. It was licensed to Glaxo in 1990 and ap...
11
Piracetam
Piracetam (sold under many brand names) is a nootropic drug in the racetams group, with chemical name 2-oxo-1-pyrrolidine acetamide. It shares the same 2-oxo-pyrrolidone base structure with pyroglutamic acid. Piracetam is a cyclic...
11
Nicotine
Nicotine is a potent parasympathomimetic alkaloid found in the nightshade family of plants (Solanaceae) and is a stimulant drug. It is made in the roots of and accumulates in the leaves of the nightshade family of plants. Nicotine...
11
Amantadine (Symmetrel)
(1966)Amantadine (trade name Symmetrel, by Endo Pharmaceuticals) is a drug that has U.S. Food and Drug Administration approval for use both as an antiviral and an antiparkinsonian drug. According to the U.S. Centers for Disease Control...
14
Duloxetine
(2004)Duloxetine (brand names Cymbalta, Yentreve, and other) is a serotonin-norepinephrine reuptake inhibitor (SNRI) created by Eli Lilly. It is mostly prescribed for major depressive disorder, generalized anxiety disorder (GAD), fibrom...
15
SAM-e
S-Adenosyl methionine (SAM-e, SAMe, SAM, S-Adenosyl-L-methionine, AdoMet, ademetionine) is a common cosubstrate involved in methyl group transfers. SAM was first discovered in Italy by G. L. Cantoni in 1952. SAM-e has been used as...
15
Vortioxetine
(2013)Vortioxetine (trade name Brintellix and Trintellix in Canada) is an atypical antidepressant (a serotonin modulator and stimulator) made by Lundbeck and Takeda. On September 30, 2013, it was approved by the U.S. FDA for the treatme...
17
Milnacipran
(1996)Milnacipran (brand names Ixel, Savella, Dalcipran, Toledomin) is a serotonin–norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. It is not approved for the clinical treatment of major depressiv...
17
Fluoxetine (Prozac)
(1987)Fluoxetine (trade names Prozac, Sarafem, Seronil, Rapiflux, Selfemra, and other) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. Fluoxetine was discovered and developed by scientists from Eli Lilly...
17
Fluvoxamine
(1983)Fluvoxamine (brand names: Faverin, Fevarin, Floxyfral, Luvox, Solvay, and other) is a medication which functions as a selective serotonin reuptake inhibitor (SSRI) and σ1 receptor agonist. Fluvoxamine is used primarily for the tre...
17
Vilazodone
(2011)Vilazodone (trade name Viibryd) is a serotonergic antidepressant developed by Clinical Data for the treatment of major depressive disorder. The chemical compound was originally developed by Merck KGaA (Germany). Vilazodone was app...
17
Citalopram
(1989)Citalopram (brand names: Celexa, Cipramil) is an antidepressant drug of the selective serotonin reuptake inhibitor (SSRI) class. It has U.S. Food and Drug Administration approval to treat major depression, which it received in 199...
22
Escitalopram
(2002)Escitalopram, brand names Lexapro and Cipralex among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is approved by the U.S. Food and Drug Administration (FDA) for the treatment of adult...
22
Levomilnacipran
(2013)Levomilnacipran (brand name Fetzima) is an antidepressant approved for the treatment of major depressive disorder in the United States. It was developed by Forest Laboratories and Pierre Fabre Group, and was approved by the Food a...
22
Venlafaxine
(1993)Venlafaxine (brand names: Effexor, Effexor XR, LanvexinTrevilor, Efectin, Oriven, Velafax, and other) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. This means it increases the concentrations...
25
Paroxetine
(1992)Paroxetine (trade name Paxil, Seroxat, Brisdelle, Pexeva, among others) is an antidepressant drug of the SSRI type. Paroxetine is used to treat major depression, obsessive-compulsive disorder, panic disorder, social anxiety, postt...
26
Sertraline
(1991)Sertraline (brand names Zoloft, Lustral, and other) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It was introduced to the market by Pfizer in 1991. Sertraline is primarily prescribed for major d...
26
Desvenlafaxine
(2008)Desvenlafaxine (brand names: Pristiq, DESFAX), also known as O-desmethylvenlafaxine, is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class developed and marketed by Wyeth (now part of Pfizer). Desven...
26
Flibanserin
(2015)Flibanserin, sold under the trade name Addyi, is a medication approved for the treatment of pre-menopausal women with hypoactive sexual desire disorder (HSDD). Flibanserin has been called a "female viagra" by the media...
26
Adderall
(1996)Adderall is a psychostimulant drug of the phenethylamine class prescribed in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. Adderall can also be used as an athletic performance and cognitive enhan...
26
Modafinil
(1994)Modafinil (brand names Modiodal, Provigil, Modavigil, Vigil, Alertec, and other) is a wakefulness-promoting agent (or eugeroic) used for treatment of wakefulness disorders such as narcolepsy, shift work sleep disorder, and excessi...
Info: The items listed below are officially not in the ranking; they're candidates that don't have the minimum number of votes (1) to officially be in yet. They're listed by the number of votes, not by the rating. Click any item to cast your vote.
candidate
Methylphenidate
(1955)Methylphenidate (brand names Ritalin, Concerta, Methylin, Medikinet, Equasym XL, Quillivant XR, Metadate, and other) is a central nervous system (CNS) stimulant of the phenethylamine and piperidine classes that is used in the trea...
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