What do you look for in Fallout 4? - Fred BC's opinion

A good game.

To be less glib: Fallout 3 and New Vegas were fun but flawed. I want a return of some of the things that made the Fallout franchise great, including

Real humor and a real Wild Wasteland-type feature
Random encounters

I also want a much tighter, coherent narrative with real stakes. That's difficult to do in an open world, and I wouldn't mind if they tapered it down somewhat to be more akin to Fallout 2.

Finally, there needs to be real challenge and interesting tactical gameplay.