Personally, I use ad blocking apps for google chrome because I prefer not to be spammed with pop-up ads.
And example of this is the nexusmods.com which is a place for video game modifications, they have an adblock detector that asks to turn off adblock, which I did, I went scrolling around for awhile on the site, then a window popped up and EXTREMELY loud music played, and my volume is always set at 10 for my laptop. So I put adblock up again.